Travel East on US-412 into Paragould. In Paragould, US-412 becomes West Kingshighway. Continue down West Kingshighway, 0.4 miles after the intersection at Highway 49, you will see Arkansas Methodist Medical Center on the right.

Coming from Jonesboro:

Travel Northeast on Highway 49 (US-49) to Paragould. At the West Kingshighway intersection in Paragould, make a right. You will see Arkansas Methodist Medical Center 0.4 miles on your right.

Coming from Marmaduke:

Travel Southwest down US-49 into Paragould. At the West Kingshighway intersection in Paragould, make a left. You will see Arkansas Methodist Medical Center 0.4 miles on your right.

Coming from Missouri:

Travel West on US-412 / MO-25 to US-412 West. You will see Arkansas Methodist Medical Center on your left approximately 11 miles after you pass the Arkansas State Line.